Table of Contents
Ulcers
Volume 2014, Article ID 326065, 5 pages
http://dx.doi.org/10.1155/2014/326065
Research Article

Giant Prepyloric Ulcer Haemorrhage: Patient Characteristics, Treatment, and Outcome in 2003–2012

Surgery Clinic of Tartu University Hospital, L. Puusepa 8, 51014 Tartu, Estonia

Received 30 September 2013; Revised 7 March 2014; Accepted 21 March 2014; Published 10 April 2014

Academic Editor: Tomasz Brzozowski

Copyright © 2014 Margot Peetsalu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Barkun, C. A. Fallone, N. Chiba et al., “A Canadian clinical practice algorithm for the management of patients with nonvariceal upper gastrointestinal bleeding,” Canadian Journal of Gastroenterology, vol. 18, no. 10, pp. 605–609, 2004. View at Google Scholar · View at Scopus
  2. R. Marmo, M. Koch, L. Cipolletta et al., “Predictive factors of mortality from nonvariceal upper gastrointestinal hemorrhage: a multicenter study,” American Journal of Gastroenterology, vol. 103, no. 7, pp. 1639–1647, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Christensen, A. Riis, M. Nørgaard, H. T. Sørensen, and R. W. Thomsen, “Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study,” BMC Geriatrics, vol. 7, article 8, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. C.-Y. Chang, M.-S. Wu, C.-T. Lee et al., “Prospective survey for the etiology and outcome of peptic ulcer bleeding: a community based study in Southern Taiwan,” Journal of the Formosan Medical Association, vol. 110, no. 4, pp. 223–229, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. P. García-Iglesias, A. Villoria, D. Suarez et al., “Meta-analysis: predictors of rebleeding after endoscopic treatment for bleeding peptic ulcer,” Alimentary Pharmacology and Therapeutics, vol. 34, no. 8, pp. 888–900, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. K. C. Thomopoulos, J. A. Mitropoulos, E. C. Katsakoulis et al., “Factors associated with failure of endoscopic injection haemostasis in bleeding peptic ulcers,” Scandinavian Journal of Gastroenterology, vol. 36, no. 6, pp. 664–668, 2001. View at Google Scholar · View at Scopus
  7. J. Lipschitz, G. R. Gecelter, M. G. Veller, J. R. Botha, and J. A. Myburgh, “Successes and failures of endoscopic injection haemostasis for bleeding peptic ulcers. A prospective clinical study,” South African Journal of Surgery, vol. 31, no. 4, pp. 132–136, 1993. View at Google Scholar · View at Scopus
  8. J. C. Padussis and T. N. Pappas, “Management of bleeding peptic ulcer disease,” in Gastrointestinal Bleeding: Practical Approach To Diagnosis and Management, A. D. Pryor, T. N. Pappas, and M. S. Branch, Eds., pp. 39–64, 2010. View at Google Scholar
  9. C. Mel Wilcox, “Features associated with painless peptic ulcer bleeding,” American Journal of Gastroenterology, vol. 92, no. 8, pp. 1289–1292, 1997. View at Google Scholar · View at Scopus
  10. P. W. Y. Chiu, E. K. W. Ng, S. K. H. Wong et al., “Surgical salvage of bleeding peptic ulcers after failed therapeutic endoscopy,” Digestive Surgery, vol. 26, no. 3, pp. 243–248, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. R. Czymek, A. Großmann, U. Roblick et al., “Surgical management of acute upper gastrointestinal bleeding: still a major challenge,” Hepato-Gastroenterology, vol. 59, no. 115, pp. 768–773, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. J. P. Hreinsson, E. Kalaitzakis, S. Gudmundsson, and E. S. Bjornsson, “Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting,” Scand J Gastroenterol, vol. 48, no. 4, pp. 439–447, 2013. View at Google Scholar
  13. S. Ishikawa, T. Inaba, M. Wato, S. Takashima, T. Mizushige, K. Izumikawa et al., “Exposed blood vessels of more than 2 mm in diameter are a risk factor for rebleeding after endoscopic clipping hemostasis for hemorrhagic gastroduodenal ulcer,” Digestive Endoscopy, vol. 25, no. 1, pp. 13–19, 2013. View at Google Scholar
  14. J. Soplepmann, A. Peetsalu, M. Peetsalu, A. Tein, and M. Juhola, “Peptic ulcer haemorrhage in Tartu county, Estonia: epidemiology and mortality risk factors,” Scandinavian Journal of Gastroenterology, vol. 32, no. 12, pp. 1195–1200, 1997. View at Google Scholar · View at Scopus
  15. D. M. Simeone, A. Hassan, and J. M. Scheiman, “Giant peptic ulcer: a surgical or medical disease?” Surgery, vol. 126, no. 3, pp. 474–478, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Lanas, M. Polo-Tomas, S. Garcia, L. A. Garcia-Rodriguez, J. L. Calleja, X. Calvet et al., “Outcomes of peptic ulcer bleeding, with high- or low-risk stigmata, following treatment with proton pump inhibitors in routine clinical practice,” Gut, vol. 61, 3, p. A380, 2012. View at Google Scholar
  17. M. H. Schoenberg, “Surgical therapy for peptic ulcer and nonvariceal bleeding,” Langenbeck's Archives of Surgery, vol. 386, no. 2, pp. 98–103, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. M.-S. Wu, H.-P. Wang, J.-T. Wang, T.-H. Wang, and J.-T. Lin, “Serum pepsinogen I and pepsinogen II, and the ratio of pepsinogen II pepsinagen II in peptic ulcer diseases: with special emphasis an the influence of the location of the ulcer crater,” Journal of Gastroenterology and Hepatology, vol. 10, no. 4, pp. 401–404, 1995. View at Google Scholar · View at Scopus
  19. A. Shiotani and D. Y. Graham, “Pathogenesis and therapy of gastric and duodenal ulcer disease,” Medical Clinics of North America, vol. 86, no. 6, pp. 1447–1466, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. M.-H. Chen, M.-S. Wu, W.-C. Lee, H.-P. Wang, and J.-T. Lin, “A multiple logistic regression analysis of risk factors in different subtypes of gastric ulcer,” Hepato-Gastroenterology, vol. 49, no. 44, pp. 589–592, 2002. View at Google Scholar · View at Scopus
  21. E. B. Newton, M. R. Versland, and T. E. Sepe, “Giant duodenal ulcers,” World Journal of Gastroenterology, vol. 14, no. 32, pp. 4995–4999, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. P. E. T. Arkkila, A. Kokkola, K. Seppälä, and P. Sipponen, “Size of the peptic ulcer in Helicobacter pylori-positive patients: association with the clinical and histological characteristics,” Scandinavian Journal of Gastroenterology, vol. 42, no. 6, pp. 695–701, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Karpouza, E. Samouilidou, S. Karagiannis et al., “Patients with duodenal ulcer have lower levels of serum cholesterol compared to other dyspeptic patients independently of Helicobacter pylori status,” Scandinavian Journal of Gastroenterology, vol. 43, no. 8, pp. 922–928, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Mizuki, M. Tatemichi, H. Nishiya et al., “Mucosal concentration of basic fibroblast growth factor in the healing process in human giant gastric ulcers,” Journal of Gastroenterology and Hepatology, vol. 19, no. 5, pp. 528–534, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. C. P. Swain, P. R. Salmon, and T. C. Northfield, “Does ulcer position influence presentation or prognosis of upper gastrointestinal bleeding?” Gut, vol. 27, p. A632, 1986. View at Google Scholar
  26. E. Brullet, R. Campo, X. Calvet, D. Coroleu, E. Rivero, and J. Simó Deu, “Factors related to the failure of endoscopic injection therapy for bleeding gastric ulcer,” Gut, vol. 39, no. 2, pp. 155–158, 1996. View at Google Scholar · View at Scopus
  27. B. J. Elmunzer, S. D. Young, J. M. Inadomi, P. Schoenfeld, and L. Laine, “Systematic review of the predictors of recurrent hemorrhage after endoscopic hemostatic therapy for bleeding peptic ulcers,” American Journal of Gastroenterology, vol. 103, no. 10, pp. 2625–2632, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Lau and J. J. Y. Sung, “From endoscopic hemostasis to bleeding peptic ulcers: strategies to prevent and treat recurrent bleeding,” Gastroenterology, vol. 138, no. 4, pp. 1252.e1–1254.e1, 2010. View at Publisher · View at Google Scholar · View at Scopus