Candida albicans and C. tropicalis Isolates from the Expired Breathes of Captive Dolphins and Their Environments in an Aquarium
Table 6
Antifungal susceptibility and genotypes of C. tropicalis isolates.
Susceptibility to antifungal drugs
MDR 1
ITSrRNA
Combined
IFM No.
Animal No.
AMPH-B
5-FC
FLCZ
ITZ
MCZ
MCFG
Accession No.
Genotype (1–11)
Accession No.
Genotype (I–V)
Genotype (A–M)
Dolphin isolates
55217
No. 1 (S)
0.25
<0.125
>64*
>8*
0.5
<0.03
AB379757
1
AB437044
I
A
55220
No. 2 (S)
0.25
<0.125
2
0.125
1
<0.03
AB379759
1
AB437046
I
A
55373
No. 2 (W)
0.5
<0.125
64*
4*
0.5
<0.03
AB379779
1
AB437066
I
A
55229
No. 5 (S)
0.25
<0.125
32+
8*
2
<0.03
AB379761
2
AB437048
II
B
55233
No. 7 (S)
0.25
<0.125
64*
4*
0.5
<0.03
AB379763
1
AB437050
I
A
55235
No. 7 (S)
0.5
<0.125
>64*
2*
1
<0.03
AB379765
3
AB437052
I
C
55269
No. 10 (S)
0.25
<0.125
>64*
>8*
0.5
0.06
AB379766
2
AB437053
II
B
55379
No. 10 (W)
0.5
<0.125
0.25
0.06
0.25
<0.03
AB379780
2
ND
ND
55277
No. 14 (S)
0.25
<0.125
64*
>8*
0.5
<0.03
AB379768
4
AB437055
I
D
55383
No. 14 (W)
0.25
<0.125
64*
2*
2
<0.03
AB379781
5
AB437067
I
E
Environmental isolates
55294
Pool-No. 1 (A) (S)
0.5
<0.125
4
0.25+
1
<0.03
AB379770
6
AB437057
I
F
55297
Pool-No. 2 (A) (S)
0.5
<0.125
16+
1*
1
<0.03
AB379772
1
AB437059
I
A
55299
Pool-No. 3 (A) (S)
0.5
<0.125
1
0.25+
1
<0.03
AB379774
1
AB437061
I
A
55301
Pool-No. 5 (B) (S)
0.5
<0.125
0.25
0.06
0.25
<0.03
AB379775
2
AB437062
II
B
55303
Pool-No. 6 (B) (S)
0.5
<0.125
0.25
0.06
0.25
0.03
AB379777
2
AB437064
II
B
55318
Sea Water (D) (S)
0.5
<0.125
0.5
0.06
0.25
<0.03
AB379778
2
AB437065
II
B
Reference isolates
5746
Clinical isolate (J)
1
<0.125
2
0.25+
0.5
<0.03
AB379783
7
AB437069
I
G
41420
Clinical isolate (J)*
0.5
<0.125
>64*
8*
0.5
<0.03
AB379785
1
AB437071
I
A
52008
Clinical isolate (J)*
0.5
<0.125
>64*
>8*
16
<0.03
AB379787
1
AB437073
I
A
52010
Clinical isolate (J)*
0.5
<0.125
>64*
>8*
8
<0.03
AB379788
8
AB437074
I
H
52013
Clinical isolate (J)*
0.5
<0.125
2
0.25+
0.25
<0.03
AB379790
9
AB437076
I
I
52938
Feline cystitis (J)
0.5
<0.125
1
0.06
0.5
<0.03
AB379791
10
AB437077
III
J
53910
Blood (J)
0.5
<0.125
0.5
0.03
0.125
<0.03
AB379794
8
AB437079
IV
K
54637
Pharynx (J)
0.5
<0.125
0.5
0.125
0.125
<0.03
AB379796
9
AB437081
I
I
54674
Pharynx (J)
0.5
0.125
2
0.125
0.5
<0.03
AB379797
8
AB437082
I
H
54675
Pharynx (J)
0.5
<0.125
1
0.125
0.25
<0.03
AB379798
9
AB437083
V
L
55049
Blood (J)
0.5
<0.125
0.5
0.25+
0.5
<0.03
AB379801
11
AB437085
I
M
55256
Ocular mycosis (J)
0.5
<0.125
>64*
2*
2
<0.03
AB379802
1
AB437086
I
A
S: collected at August 2006, W: collected at February 2007, J: Japan. A, B, C and D indicated at the environmental isolate indicated the water supply system. AMPH-B: amphotericin B, 5-FC: flucytosine, FLCZ: fluconazole, ITZ: itraconazole, MCZ: miconazole, MCFG: micafungin,
*; resistant, and +; dose-dependent susceptibility based on CLSI M27-A2 protocol [42].
