Antioxidants and the Integrity of Ocular Tissues

Table 2

Animal research comparing antioxidants and/or plasma levels of antioxidants molecules with degenerative changes in dogs.

Authors	Objective	Antioxidants	Conclusion
Barros et al. (1999) [49]	To determine the erythrocytic enzymatic antioxidants, plasma Vit. C and MDA in normal and cataractous English Cocker Spaniel dogs.	Enzymes: SOD, CAT, GPx, and G6PD.; Vit. C.	Decrease levels of plasma Vit. C are related with cataract.
Barros et al. (2003) [32]	To determined the antioxidant status of the aqueous humor after extracapsular lens extraction.	Total antioxidant status and Vit C.	Lens surgical procedures reduced total antioxidant status and Vit. C levels.
Barros et al. (2004) [69]	To determined levels of enzymatic and nonenzymatic antioxidants in blood and aqueous humor of cataractous and noncataractous poodles.	Enzymes: SOD, CAT, GPx, and G6PD.; Vit. C.	Activity of SOD, G6PD, and CAT was significantly higher in noncataractous poodles than in cataractous poodles. There was no difference in mean plasma Vit. C concentration between cataractous and noncataractous dogs.
De Biaggi et al. (2006) [48]	To determined the antioxidant status of the aqueous humor after phacoemulsification.	Total antioxidant status and Vit. C.	Lens surgical procedures reduced total antioxidant status and Vit. C levels.

Vit. C: vitamin C; GPx: glutathione peroxidase; SOD: superoxide dismutase; CAT: catalase; MDA: malondialdehyde; G6PD: glucose-6-phosphate dehydrogenase.