Research Article

A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis

Table 2

Isolation of M. bovis from a range of tissues taken from 4 ferrets infected with CFU and examined postmortem at 8 weeks post infection.

Tag number349358728884
TissueLS1QL2QN3LSQLQNLSQLQNLSQLQN

Submandibular LN0+000
Retropharyngeal LNNS4NSNS0NSNSNS0
Mesenteric LN1+2+1+1+
Upper left lung1+0+2+2+
Lower left lung2+341+2+0
Upper right lung2+21.60+2+0
Lower right lung2+21.72+3+2+
Lung associated LN0+52.32+2+72+
Kidney0000.220
Liver038.500+26.30
Spleen2+51.11+0+0.1902.31

1LS: lesion score.
2QL: qualitative bacteriology.
3QN: quantitative bacteriology (×102 CFU/g).
4NS: not sampled.