Research Article
A New Experimental Infection Model in Ferrets Based on Aerosolised Mycobacterium bovis
Table 2
Isolation of
M. bovis from a range of tissues taken from 4 ferrets infected with
CFU and examined postmortem at 8 weeks post infection.
| Tag number | 349 | 358 | 728 | 884 | Tissue | LS1 | QL2 | QN3 | LS | QL | QN | LS | QL | QN | LS | QL | QN |
| Submandibular LN | 0 | + | − | 0 | − | − | 0 | − | − | 0 | − | − | Retropharyngeal LN | NS4 | NS | NS | 0 | − | − | NS | NS | NS | 0 | − | − | Mesenteric LN | 1 | + | − | 2 | + | − | 1 | + | − | 1 | + | − | Upper left lung | 1 | + | − | 0 | + | − | 2 | + | − | 2 | + | − | Lower left lung | 2 | + | 34 | 1 | + | − | 2 | + | − | 0 | − | − | Upper right lung | 2 | + | 21.6 | 0 | + | − | 2 | + | − | 0 | − | − | Lower right lung | 2 | + | 21.7 | 2 | + | − | 3 | + | − | 2 | + | − | Lung associated LN | 0 | + | 52.3 | 2 | + | − | 2 | + | 7 | 2 | + | − | Kidney | 0 | − | − | 0 | − | − | 0 | − | 0.22 | 0 | − | − | Liver | 0 | − | 38.5 | 0 | − | − | 0 | + | 26.3 | 0 | − | − | Spleen | 2 | + | 51.1 | 1 | + | − | 0 | + | 0.19 | 0 | − | 2.31 |
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1LS: lesion score. 2QL: qualitative bacteriology. 3QN: quantitative bacteriology (×102 CFU/g). 4NS: not sampled.
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