Single Intramammary Infusion of Recombinant Bovine Interleukin-8 at Dry-Off Induces the Prolonged Secretion of Leukocyte Elastase, Inflammatory Lactoferrin-Derived Peptides, and Interleukin-8 in Dairy Cows

Table 1

Milk clot formation; PMNL count; elastase activity; concentrations of IL-8, 22 and 23 kDa LDP, and Lf in mammary secretions from the uninfected and infected quarters of cows with S. aureus dry-period mastitis.

	Quarter
	Uninfected (𝑛=21)	Infected (𝑛=7)
S. aureus (log10 cfu/mL)	ND^1	3.19±0.17
Milk clot formation (number of quarters)	0	7
PMNL (log10 count/mL)	6.18±0.04	> 8.0^2
Elastase (units/mL)	ND	0.58±0.11
IL-8 (pg/mL)	ND	1840±581
22 and 23 kDa LDP (μg/mL)	1.49±0.39	35.7±4.6^3
Lf (mg/mL)	9.70±0.23	3.53±0.28^3

¹Not detectable.
²Due to the presence of milk clots, PMNL counts could not be precisely determined. PMNL counts of more than 10⁸ cells/mL were excluded.
³Significantly different compared to the uninfected quarters.