Table of Contents Author Guidelines Submit a Manuscript
Veterinary Medicine International
Volume 2012 (2012), Article ID 798502, 13 pages
http://dx.doi.org/10.1155/2012/798502
Research Article

Bovine Tuberculosis in Cattle in the Highlands of Cameroon: Seroprevalence Estimates and Rates of Tuberculin Skin Test Reactors at Modified Cut-Offs

1School of Veterinary Medicine and Sciences, University of Ngaoundere, Ngaoundere, Adamawa Region, Cameroon
2Department of Animal Sciences, University of Dschang, Dschang, West Region, Cameroon
3School of Biomedical and Biological Sciences, University of Plymouth, Plymouth, PL4 8AA, UK
4Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
5Institute of Agricultural research for Development (IRAD), Wakwa- Ngaoundere, Adamawa Region, Cameroon
6Institute of Animal Breeding and Husbandry, University of Kiel, Kiel, Germany
7Department of Mathematics and Computer Science, University of Dschang, Dschang, West Region, Cameroon
8Heifer Project International, P.O. Box 467, Bamenda, North West Region, Cameroon
9Delegation of Livestock, Fisheries and Animal Husbandry, North West Region, Cameroon

Received 19 October 2011; Revised 10 January 2012; Accepted 22 January 2012

Academic Editor: Jesse M. Hostetter

Copyright © 2012 J. Awah-Ndukum et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to obtain epidemiological estimates of bovine tuberculosis (TB) prevalence in cattle in the highlands of Cameroon using two population-based tuberculin skin test (TST) surveys in the years 2009 and 2010. However, prior to the TST survey in 2010, blood was collected from already chosen cattle for serological assay. Anti-bovine TB antibodies was detected in 37.17% of tested animals and bovine TB prevalence estimates were 3.59%–7.48%, 8.92%–13.25%, 11.77%–17.26% and 13.14%–18.35% for comparative TST at ≥4 mm, ≥3 mm and ≥2 mm cut-off points and single TST, respectively. The agreement between TST and lateral flow was generally higher in TST positive than in TST negative subjects. The coefficients were 0.119, 0.234, 0.251 and 0.254 for comparative TST at ≥4 mm, ≥3 mm and ≥2 mm cut-off points and the single TST groups, respectively. Chi square statistics revealed that strong ( ; ) associations existed between seroprevalence rates and TST reactors. The study suggested that using lateral flow assay and TST at severe interpretations could improve the perception of bovine TB in Cameroon. The importance of defining TST at modified cut-offs and disease status by post-mortem detection and mycobacterial culture of TB lesions in local environments cannot be overemphasised.