E. coli-Derived L-Asparaginase Retains Enzymatic and Cytotoxic Activity In Vitro for Canine and Feline Lymphoma after Cold Storage
Figure 6
Effect of refrigeration on asparaginase enzyme activity. There is no significant difference in asparaginase activity between refrigeration and freshly reconstituted drug or with duration of refrigeration, . As expected, asparaginase concentration has a significant effect on enzyme activity (), but no difference between cold storage types at any concentration tested. This verifies that refrigerated drug retains enzyme activity at 7 and 14 days similar to freshly prepared drug.
