Research Article

Effects of Acute Bleeding Followed by Hydroxyethyl Starch 130/0.4 or a Crystalloid on Propofol Concentrations, Cerebral Oxygenation, and Electroencephalographic and Haemodynamic Variables in Pigs

Table 3

Suppression ratio (SR: %), total power ( : μV), spectral edge frequency (SEF: Hz), bispectral index (BIS), approximate entropy (AE), permutation entropy (PE), SR corrected SEF (SRSEF: Hz), and SR corrected PE (SRPE) at each study phase: A: right before the start of bleeding; B: in the end of bleeding/start of the waiting period; C: in the end of the waiting period/start of the volume replacement period); D: in the end of the volume replacement period/start of the final phase; and E: in the end of the study. GLR: group that received lactated Ringer’s for volume replacement; GHES: group that received hydroxyethyl starch for volume replacement. Mean ± standard deviation is shown. The number of animals ( ) in each group for each parameter is shown.

SR (%)TPEEG (μV) SEF (Hz)BISAEPESRSEF (Hz)SRPE
GLR  
( )
GHES  
( )
GLR  
( )
GHES  
( )
GLR  
( )
GHES  
( )
GLR  
( )
GHES  
( )
GLR  
( )
GHES  
( )
GLR  
( )
GHES  
( )
GLR  
(
GHES  
(
GLR  
(
GHES  
(

A0.0 ± 0.05.9 ± 14.459.4 ± 3.359.6 ± 5.314.9 ± 0.914.9 ± 1.364.2 ± 5.755.8 ± 7.70.74 ± 0.150.76 ± 0.120.86 ± 0.090.84 ± 0.0914.9 ± 0.913.9 ± 1.30.86 ± 0.090.79 ± 0.16
B0.23 ± 0.567.1 ± 16.9 14.7 ± 1.515.4 ± 1.9 0.82 ± 0.130.77 ± 0.130.87 ± 0.090.85 ± 0.1014.7 ± 1.614.1 ± 1.70.87 ± 0.090.79 ± 0.18
C2.5 ± 5.111.9 ± 29.1 15.6 ± 1.315.6 ± 0.859.6 ± 5.855.1 ± 21.40.84 ± 0.120.76 ± 0.15 15.1 ± 0.913.8 ± 4.50.87 ± 0.100.74 ± 0.25
D0.15 ± 0.3413.6 ± 33.3 14.9 ± 0.615.1 ± 1.563.3 ± 4.451.9 ± 22.10.83 ± 0.120.78 ± 0.12 14.9 ± 0.512.2 ± 4.40.85 ± 0.090.72 ± 0.29
E0.0 ± 0.09.7 ± 23.757.8 ± 3.258.3 ± 5.815.6 ± 1.215.0 ± 1.263.1 ± 3.553.2 ± 18.00.82 ± 0.140.77 ± 0.150.86 ± 0.090.84 ± 0.0915.6 ± 1.213.3 ± 3.10.86 ± 0.090.76 ± 0.22

Significantly different from the previous measurement: , level.