Table of Contents Author Guidelines Submit a Manuscript
Veterinary Medicine International
Volume 2015 (2015), Article ID 932080, 8 pages
http://dx.doi.org/10.1155/2015/932080
Research Article

Effect of Moxidectin Treatment at Peripartum on Gastrointestinal Parasite Infections in Ewes Raised under Tropical Andes High Altitude Conditions

1Genetic Institute, National University of Colombia, Carrera 30 No. 45-03, Edificio 426, Bogotá D.C., Colombia
2Unit of Integrated Veterinary Research, Department of Veterinary Medicine, University of Namur, rue de Bruxelles 61, 5000 Namur, Belgium
3Faculty of Veterinary Medicine and Animal Science, National University of Colombia, Carrera 30 No. 45-03, Edificio 481, Bogotá D.C., Colombia
4Faculty of Veterinary Medicine, Cooperative University of Colombia, Calle 30 No. 33-51, Bucaramanga, Colombia
5Research Unit of Epidemiology and Risk Analysis Applied to Veterinary Sciences (UREAR), Fundamental and Applied Research for Animal and Health (FARAH), University of Liège, boulevard de Colonster 20, 4000 Liège, Belgium

Received 19 January 2015; Revised 15 April 2015; Accepted 22 April 2015

Academic Editor: Guillermo Virkel

Copyright © 2015 J. J. Vargas-Duarte et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Gaba, J. Cabaret, C. Chylinski, C. Sauvé, J. Cortet, and A. Silvestre, “Can efficient management of sheep gastro-intestinal nematodes be based on random treatment?” Veterinary Parasitology, vol. 190, no. 1-2, pp. 178–184, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. M. R. Knox, R. B. Besier, L. F. Le Jambre et al., “Novel approaches for the control of helminth parasites of livestock VI: summary of discussions and conclusions,” Veterinary Parasitology, vol. 186, no. 1-2, pp. 143–149, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. D. M. Leathwick and R. B. Besier, “The management of anthelmintic resistance in grazing ruminants in Australasia—strategies and experiences,” Veterinary Parasitology, vol. 204, no. 1-2, pp. 44–54, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. J. B. da Silva, C. P. Rangel, B. de Azevedo Baêta, and A. H. da Fonseca, “Risk factors relating to helminth infections in cows during the peripartum,” Revista Brasileira de Parasitologia Veterinaria, vol. 21, no. 2, pp. 92–96, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. V. Goldberg, G. Ciappesoni, and I. Aguilar, “Modelling the faecal worm egg count curve during the periparturient period in uruguayan merino sheep,” Spanish Journal of Agricultural Research, vol. 10, no. 4, pp. 986–992, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. I. G. Colditz, D. L. Watson, G. D. Gray, and S. J. Eady, “Some relationships between age, immune responsiveness and resistance to parasites in ruminants,” International Journal for Parasitology, vol. 26, no. 8-9, pp. 869–877, 1996. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Tembely, A. Lahlou-Kassi, J. E. O. Rege et al., “Breed and season effects on the peri-parturient rise in nematode egg output in indigenous ewes in a cool tropical environment,” Veterinary Parasitology, vol. 77, no. 2-3, pp. 123–132, 1998. View at Publisher · View at Google Scholar · View at Scopus
  8. N. D. Sargison, “Pharmaceutical treatments of gastrointestinal nematode infections of sheep—future of anthelmintic drugs,” Veterinary Parasitology, vol. 189, no. 1, pp. 79–84, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. L. P. Kahn, M. R. Knox, and G. D. Gray, “Enhancing immunity to nematode parasites in pregnant and lactating sheep through nutrition and genetic selection,” in Recent Advances in Animal Nutrition in Australia, J. L. Corbett, Ed., vol. 12, pp. 15–22, University of New England, Armidale, Australia, 1999. View at Google Scholar
  10. P. Sakkas, J. G. M. Houdijk, S. Athanasiadou, and I. Kyriazakis, “Sensitivity of periparturient breakdown of immunity to parasites to dietary protein source,” Journal of Animal Science, vol. 90, no. 11, pp. 3954–3962, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. A. M. Beasley, L. P. Kahn, and R. G. Windon, “The periparturient relaxation of immunity in Merino ewes infected with Trichostrongylus colubriformis: endocrine and body compositional responses,” Veterinary Parasitology, vol. 168, no. 1-2, pp. 51–59, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. A. C. Kotze, B. M. Hines, and A. P. Ruffell, “A reappraisal of the relative sensitivity of nematode pharyngeal and somatic musculature to macrocyclic lactone drugs,” International Journal for Parasitology: Drugs and Drug Resistance, vol. 2, pp. 29–35, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. A. R. Sykes, “Environmental effects on animal production: the nutritional demands of nematode parasite exposure in sheep,” Asian-Australasian Journal of Animal Sciences, vol. 13, pp. 343–350, 2000. View at Google Scholar · View at Scopus
  14. F. A. Macarthur, L. P. Kahn, and R. G. Windon, “Immune response of twin-bearing Merino ewes when infected with Haemonchus contortus: effects of fat score and prepartum supplementation,” Livestock Science, vol. 157, no. 2-3, pp. 568–576, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. A. R. Williams, J. C. Greeff, P. E. Vercoe, R. J. Dobson, and L. J. E. Karlsson, “Merino ewes bred for parasite resistance reduce larval contamination onto pasture during the peri-parturient period,” Animal, vol. 4, no. 1, pp. 122–127, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. N. D. Sargison, D. J. Bartram, and D. J. Wilson, “Use of a long acting injectable formulation of moxidectin to control the periparturient rise in faecal Teladorsagia circumcincta egg output of ewes,” Veterinary Parasitology, vol. 189, no. 2–4, pp. 274–283, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. L. P. Kahn, M. R. Knox, G. D. Gray, J. M. Lea, and S. W. Walkden-Brown, “Enhancing immunity to nematode parasites in single-bearing Merino ewes through nutrition and genetic selection,” Veterinary Parasitology, vol. 112, no. 3, pp. 211–225, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. A. M. Beasley, L. P. Kahn, and R. G. Windon, “The influence of reproductive physiology and nutrient supply on the periparturient relaxation of immunity to the gastrointestinal nematode Trichostrongylus colubriformis in Merino ewes,” Veterinary Parasitology, vol. 188, no. 3-4, pp. 306–324, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. L. A. Jones, P. Sakkas, J. G. M. Houdijk, D. P. Knox, and I. Kyriazakis, “Amelioration of the periparturient relaxation of immunity to parasites through a reduction in mammalian reproductive effort,” International Journal for Parasitology, vol. 42, no. 13-14, pp. 1127–1134, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. F. J. McPherson, S. Shini, A. W. Gibbon, and M. J. D'Occhio, “Protein supplementation in the first 100 days of gestation fails to enhance resistance of weaned Merino lambs against Haemonchus contortus,” Livestock Science, vol. 150, no. 1–3, pp. 11–21, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. F. A. Macarthur, L. P. Kahn, and R. G. Windon, “Regulating maternal production of twin-bearing Merino ewes through fat score and prepartum supplementation when infected with Haemonchus contortus,” Livestock Science, vol. 157, no. 2-3, pp. 442–451, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. V. H. Suarez, “Helminthic control on grazing ruminants and environmental risks in South America,” Veterinary Research, vol. 33, no. 5, pp. 563–573, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. M. B. Molento, F. S. Fortes, D. A. S. Pondelek et al., “Challenges of nematode control in ruminants: focus on Latin America,” Veterinary Parasitology, vol. 180, no. 1-2, pp. 126–132, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. A. N. Henrioud, “Towards sustainable parasite control practices in livestock production with emphasis in Latin America,” Veterinary Parasitology, vol. 180, no. 1-2, pp. 2–11, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. J. F. Torres-acosta, R. I. Rodríguez-Vivas, and R. Cámara-Sarmiento, “Efecto del parto sobre la eliminación de huevecillos de nemátodos y ooquistes de Eimeria en cabras criollas,” Revista Biomédica, vol. 6, no. 4, pp. 208–215, 1995. View at Google Scholar
  26. E. Romjali, A. Batubara, V. S. Pandey, and R. M. Gatenby, “Short communication Peri-parturient rise in faecal strongyle egg counts of different genotypes of sheep in North Sumatra, Indonesia,” Veterinary Parasitology, vol. 68, no. 1997, pp. 191–196, 2000. View at Google Scholar
  27. N. Mandonnet, M. Bachand, M. Mahieu et al., “Impact on productivity of peri-parturient rise in fecal egg counts in Creole goats in the humid tropics,” Veterinary Parasitology, vol. 134, no. 3-4, pp. 249–259, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Mahieu and G. Aumont, “Periparturient rise in Martinik Hair Sheep and perspectives for gastrointestinal nematode control,” Tropical Animal Health and Production, vol. 39, no. 6, pp. 387–390, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. D. C. Moreno-Vargas and H. A. Grajales-Lombana, “Caracterización del proceso administrativo y de mercado en los sistemas ovinos del trópico alto colombiano,” Revista Cienci Animal, no. 7, pp. 85–98, 2014. View at Google Scholar
  30. M. Knox and J. Steel, “Nutritional enhancement of parasite control in small ruminant production systems in developing countries of south-east Asia and the Pacific,” International Journal for Parasitology, vol. 26, no. 8-9, pp. 963–970, 1996. View at Publisher · View at Google Scholar · View at Scopus
  31. R. A. Rocha, A. F. T. Amarante, and P. A. Bricarello, “Comparison of the susceptibility of Santa Inês and Ile de France ewes to nematode parasitism around parturition and during lactation,” Small Ruminant Research, vol. 55, no. 1–3, pp. 65–75, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. G. Morales, E. Sandoval, L. A. Pino, and Z. Rondón, “Evaluación de dos criterios de utilidad en un programa de control de la infección por nematodos gastrointestinales en ovinos mediante tratamiento antihelmíntico selectivo,” Zootecnia Tropical, vol. 26, no. 2, pp. 141–150, 2008. View at Google Scholar
  33. M. Tibbo, K. Aragaw, J. Philipsson et al., “A field trial of production and financial consequences of helminthosis control in sheep production in Ethiopia,” Preventive Veterinary Medicine, vol. 84, no. 1-2, pp. 152–160, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. G. Cringoli, L. Rinaldi, V. Veneziano, L. Mezzino, J. Vercruysse, and F. Jackson, “Evaluation of targeted selective treatments in sheep in Italy: effects on faecal worm egg count and milk production in four case studies,” Veterinary Parasitology, vol. 164, no. 1, pp. 36–43, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. P. Godoy, J. Lian, R. N. Beech, and R. K. Prichard, “Haemonchus contortus P-glycoprotein-2: in situ localisation and characterisation of macrocyclic lactone transport,” International Journal for Parasitology, vol. 45, no. 1, pp. 85–93, 2015. View at Publisher · View at Google Scholar
  36. M. Lloberas, L. Alvarez, C. Entrocasso et al., “Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: impact of drug treatments on parasite P-glycoprotein expression,” International Journal for Parasitology: Drugs and Drug Resistance, vol. 3, pp. 20–27, 2013. View at Publisher · View at Google Scholar · View at Scopus
  37. D. Márquez, G. Jiménez, F. García, and C. Garzón, “Resistencia a los antihelmínticos en nemátodos gastrointestinales de bovinos en municipios de Cundinamarca y Boyacá,” Corpoica Ciencia y Tecnología Agropecuaria, vol. 9, no. 1, pp. 113–123, 2008. View at Google Scholar
  38. J. M. Broughan and R. Wall, “Faecal soiling and gastrointestinal helminth infection in lambs,” International Journal for Parasitology, vol. 37, no. 11, pp. 1255–1268, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. A. Di Loria, V. Veneziano, D. Piantedosi et al., “Evaluation of the FAMACHA system for detecting the severity of anaemia in sheep from southern Italy,” Veterinary Parasitology, vol. 161, no. 1-2, pp. 53–59, 2009. View at Publisher · View at Google Scholar · View at Scopus
  40. S. A. Henriksen and J. P. Christensen, “Demonstration of Isospora suis oocysts in faecal samples,” Veterinary Record, vol. 131, no. 19, pp. 443–444, 1992. View at Google Scholar · View at Scopus
  41. R. J. Dobson, B. C. Hosking, C. L. Jacobson et al., “Preserving new anthelmintics: a simple method for estimating faecal egg count reduction test (FECRT) confidence limits when efficacy and/or nematode aggregation is high,” Veterinary Parasitology, vol. 186, no. 1-2, pp. 79–92, 2012. View at Publisher · View at Google Scholar · View at Scopus
  42. G. C. Coles, C. Bauer, F. H. M. Borgsteede et al., “World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance,” Veterinary Parasitology, vol. 44, no. 1-2, pp. 35–44, 1992. View at Publisher · View at Google Scholar · View at Scopus
  43. P. R. Torgerson, M. Paul, and R. Furrer, “Evaluating faecal egg count reduction using a specifically designed package ‘eggCounts’ in R and a user friendly web interface,” International Journal for Parasitology, vol. 44, no. 5, pp. 299–303, 2014. View at Publisher · View at Google Scholar · View at Scopus
  44. F. Kenyon, A. W. Greer, G. C. Coles et al., “The role of targeted selective treatments in the development of refugia-based approaches to the control of gastrointestinal nematodes of small ruminants,” Veterinary Parasitology, vol. 164, no. 1, pp. 3–11, 2009. View at Publisher · View at Google Scholar · View at Scopus
  45. A. M. Beasley, L. P. Kahn, and R. G. Windon, “The periparturient relaxation of immunity in Merino ewes infected with Trichostrongylus colubriformis: parasitological and immunological responses,” Veterinary Parasitology, vol. 168, no. 1-2, pp. 60–70, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. F. A. Imperiale, M. R. Busetti, V. H. Suárez, and C. E. Lanusse, “Milk excretion of ivermectin and moxidectin in dairy sheep: assessment of drug residues during cheese elaboration and ripening period,” Journal of Agricultural and Food Chemistry, vol. 52, no. 20, pp. 6205–6211, 2004. View at Publisher · View at Google Scholar · View at Scopus
  47. J. A. van Wyk, “Refugia—overlooked as perhaps the most potent factor concerning the development of anthelmintic resistance,” Onderstepoort Journal of Veterinary Research, vol. 68, no. 1, pp. 55–67, 2001. View at Google Scholar · View at Scopus
  48. M. Dever and L. Kahn, “Decline in faecal worm egg counts in lambs suckling ewes treated with lipophilic anthelmintics: Implications for hastening development of anthelmintic resistance,” Veterinary Parasitology, vol. 209, no. 3-4, pp. 229–234, 2015. View at Publisher · View at Google Scholar