Table of Contents
X-Ray Optics and Instrumentation
Volume 2008 (2008), Article ID 709692, 17 pages
Research Article

High-Definition X-Ray Fluorescence: Applications

X-Ray Optical Systems, Inc. 15 Tech Valley Drive, East Greenbush, NY 12061, USA

Received 5 March 2008; Accepted 14 July 2008

Academic Editor: Ladislav Pina

Copyright © 2008 Walter M. Gibson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Energy dispersive X-ray fluorescence (EDXRF) is a well-established and powerful tool for nondestructive elemental analysis of virtually any material. It is widely used for environmental, industrial, pharmaceutical, forensic, and scientific research applications to measure the concentration of elemental constituents or contaminants. The fluorescing atoms can be excited by energetic electrons, ions, or photons. A particular EDXRF method, monochromatic microbeam X-ray fluorescence (MμEDXRF), has proven to be remarkably powerful in measurement of trace element concentrations and distributions in a large variety of important medical, environmental, and industrial applications. When used with state-of-the-art doubly curved crystal (DCC) X-ray optics, this technique enables high-sensitivity, compact, low-power, safe, reliable, and rugged analyzers for insitu, online measurements in industrial process, clinical, and field settings. This new optic-enabled MμEDXRF technique is known as high-definition X-Ray fluorescence (HD XRF). Selected applications of HD XRF are described in this paper including air particulate analysis, analysis of body fluid contamination at ppb levels, elemental mapping of brain tissue and bone samples, as well as analysis of toxins in toys and other consumer products.