Evaluation of the Therapeutic Effect of the Traditional Herbal Medicine Atrifil and Oshagh Gum on Testosterone-Induced Benign Prostatic Hyperplasia in Wistar Rats

Figure 6

Interaction between amino acids in the binding site of 5α-reductase enzyme, and (a) = equol, (b) = finasteride, (c) = kaempferol, (d) = quercetin, and (e) = rutin, respectively. The green bonds show intramolecular hydrogen bonds. Arginine, aspartic acid, alanine, glutamic acid, tyrosine, isoleucine, alanine, and serine are involved in H-bond interaction between ligands and receptors.