Evaluation of the Therapeutic Effect of the Traditional Herbal Medicine Atrifil and Oshagh Gum on Testosterone-Induced Benign Prostatic Hyperplasia in Wistar Rats

Table 4

Binding affinity of the finasteride, equol, kaempferol, quercetin, and rutin to 5α-reductase, estrogen receptor alpha and beta, and estrogen-related receptor gamma.

Substance	5α-reductase (kcal/mol)	ER-a (kcal/mol)	ER-b (kcal/mol)	Estrogen-related receptor gamma (kcal/mol)
Finasteride	−9.2	−6.2	−7.1	−6.9
Equol	−9.1	−5.9	−7.5	−7.2
Kaempferol	−9.2	−2.7	−6.2	−5.8
Quercetin	−9.6	−6.9	−7.7	−6.6
Rutin	−10.6	+13.4	−7.7	−7.4