Research Article

The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats

Table 4

Effect of treating diabetic rats with Moringa seeds powder for 4 weeks on kidney functions and serum electrolytes.

Parameters
mg/dL
Statistics G1
−ve control
G2
+ve control
G3
50 mg
Moringa
G4
100 mg
Moringa

Blood urea nitrogen
mg/dL
Mean ± SE
LSD 0.05 = 4.479
23.83 ± 1.13a68.33 ± 1.40d52.50 ± 1.60b34.16 ± 1.04c
-test−20.47.414.3

Creatinine
mg/dL
Mean ± SE
LSD 0.05 = 0.264
0.65 ± 0.04a2.78 ± 0.15d2.08 ± 0.06b1.53 ± 0.04c
-test−13.44.17.8

Uric acid
mg/dL
Mean ± SE
LSD 0.05 = 0.196
3.33 ± 0.06c6.20 ± 0.10a4.35 ± 0.04b4.16 ± 0.04b
-test−26.425.716.1

Sodium
mmol/L
Mean ± SE
LSD 0.05 = 2.402
121.83 ± 0.65a141.00 ± 0.81d128.00 ± 0.68c136.17 ± 0.70b
-test18.9−5.0−13.5

Potassium
mmol/L
Mean ± SE
LSD 0.05 = 0.158
3.40 ± 0.03a4.76 ± 0.05d3.80 ± 0.05c4.18 ± 0.06b
-test14.8−4.6−11.1

Data are represented as mean ± SE. -test values; < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c, or d) are significantly different at < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at < 0.05. LSD: least significant difference.