Plasminogen Activator Inhibitor-Type I Gene Deficient Mice Show Reduced Influx of Neutrophils in Ventilator-Induced Lung Injury

Figure 3

Wet-to-dry ratios (W/D) of the left lung, total protein level in BALF, and number of neutrophils in BALF in anesthetized nonventilated control (C) mice, mice ventilated with LV_T or HV_T. Mice were either PAI-1 deficient (PAI-1^−/−, open symbols) or wild type (Wt, closed symbols). Data are represented as individual data with a median. * indicates statistical significant difference compared to Wt.

(a)

(b)

(c)