Quantitative Anti-HBc in Liver Pathological States in Patients with Chronic Hepatitis B Virus Infection
Table 2
Differences in Spearman correlation coefficients among serum and intrahepatic HBV markers with pathological grades and stages.
Variable
HBeAg-positive (n = 254)
HBeAg-negative (n = 237)
Pathological grade
Pathological stage
Pathological grade
Pathological stage
rs
rs
rs
rs
Serum anti-HBc
0.312ab
<0.0001
0.268c
<0.0001
0.270d
<0.0001
0.147e
0.0237
Serum HBsAg
−0.248
0.0001
−0.272
<0.0001
0.183
0.0046
0.127
0.0503
Serum HBV DNA
−0.073a
0.2470
−0.128
0.0410
0.493d
<0.0001
0.411e
<0.0001
Intrahepatic HBsAg
0.017b
0.7825
0.030c
0.6380
0.212
0.0010
0.221
0.0006
Intrahepatic HBcAg
−0.270
<0.0001
−0.254
<0.0001
0.220
0.0007
0.169
0.0093
a–ePairwise comparisons between different Spearman correlation coefficients, , by Fisher’s Z test. a: Z = 2.797, ; b: Z = 3.425, ; c: Z = 2.741, ; d: Z = 2.846, ; e: Z = 3.123, .