Spoligotype Variation of Mycobacterium tuberculosis Strains Prevailing in Korea
Table 1
Strain distribution according to genomic families and clusters in Korea from 1994 to 2006.
Lineage
Genomic family (no. of subfamilies)
Number of strains (%)
No. of clusters (no. of clustered strains)
The dominant clusters SIT no.
No. of strains per dominant cluster (%)
Lineage 2
Beijing (2)
767 (72.7)
8 (762)
1
648 (61.4)
Lineage 4
T (6)
209 (19.8)
14 (184)
53
113 (10.7)
H (2)
12 (1.1)
2 (7)
50
5 (0.5)
LAM (2)
3 (0.3)
1 (2)
388
2 (0.2)
S (1)
2 (0.2)
1 (2)
125
2 (0.2)
Ural-1 (1)
1 (0.1)
—
X (2)
4 (0.4)
1 (3)
92
3 (0.3)
Lineage 1
Manu (2)
6 (0.6)
1 (4)
54
4 (0.4)
Lineage 3
CAS (2)
4 (0.4)
—
—
—
Unknown
New (—)
13 (1.2)
2 (8)
773 (5)
5 (0.5)
Not defined
Orphan (—)
34 (3.2)
3 (8)
K7 (3), K25 (3)
3 (0.3), 3 (0.3)
Total
1055 (100)
33 (980)
788 (74.7)
SIT, shared international type from international spoligotype database SITVIT2 (http://www.pasteur-guadeloupe.fr:8081/SITVIT2).Provisionally numbered unique orphan strains in this study.