Research Article

Spoligotype Variation of Mycobacterium tuberculosis Strains Prevailing in Korea

Table 1

Strain distribution according to genomic families and clusters in Korea from 1994 to 2006.

LineageGenomic family (no. of subfamilies)Number of strains (%)No. of clusters (no. of clustered strains)The dominant clusters SIT no.No. of strains per dominant cluster (%)

Lineage 2Beijing (2)767 (72.7)8 (762)1648 (61.4)
Lineage 4T (6)209 (19.8)14 (184)53113 (10.7)
H (2)12 (1.1)2 (7)505 (0.5)
LAM (2)3 (0.3)1 (2)3882 (0.2)
S (1)2 (0.2)1 (2)1252 (0.2)
Ural-1 (1)1 (0.1)
X (2)4 (0.4)1 (3)923 (0.3)
Lineage 1Manu (2)6 (0.6)1 (4)544 (0.4)
Lineage 3CAS (2)4 (0.4)
UnknownNew (—)13 (1.2)2 (8)773 (5)5 (0.5)
Not definedOrphan (—)34 (3.2)3 (8)K7 (3), K25 (3)3 (0.3), 3 (0.3)
Total1055 (100)33 (980)788 (74.7)

SIT, shared international type from international spoligotype database SITVIT2 (http://www.pasteur-guadeloupe.fr:8081/SITVIT2).Provisionally numbered unique orphan strains in this study.