Molecular Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae in a Tertiary Hospital in Northern China

Table 2

The antimicrobial resistance profiles of 45 CRKP isolates.

Antibiotic	CRKP (n = 45)	ST11 (n = 22)	Others-ST (n = 23)	value	ICU (n = 22)	Non-ICU (n = 23)	value
	Total resistance rate (%)	Resistance rate (%)	Resistance rate (%)		Resistance rate (%)	Resistance rate (%)
TZP	77.80	68.20	87.00	0.001	72.70	82.60	0.088
AMC	100.00	100.00	100.00	—	100.00	100.00	—
SCF	100.00	100.00	100.00	—	100.00	100.00	—
CFZ	100.00	100.00	100.00	—	100.00	100.00	—
CXM	100.00	100.00	100.00	—	100.00	100.00	—
CRO	100.00	100.00	100.00	—	100.00	100.00	—
FEP	77.80	72.70	82.60	0.088	72.70	82.60	0.088
FOX	71.10	63.60	78.30	0.029	63.60	78.30	0.029
IPM	100.00	100.00	100.00	—	100.00	100.00	—
MEM	100.00	100.00	100.00	—	100.00	100.00	—
ETP	100.00	100.00	100.00	—	100.00	100.00	—
GEN	40.00	31.80	47.80	0.021	40.90	39.10	0.773
AMK	22.20	31.80	13.00	0.001	27.30	17.40	0.088
ATM	93.30	100.00	87.00	<0.001	100.00	87.00	<0.001
TOB	35.60	31.80	39.10	0.301	40.90	30.40	0.104
CIP	91.10	100.00	82.60	<0.001	100.00	82.60	<0.001
LEV	77.80	100.00	56.50	<0.001	90.90	65.20	<0.001
SXT	60.00	50.00	69.60	0.004	63.60	56.50	0.273
TGC	6.70	4.50	8.70	0.268	4.50	8.70	0.268
COL	11.10	9.10	13.00	0.366	4.50	17.40	0.007

TZP, piperacillin/tazobactam; AMC, amoxicillin/clavulanic acid; SCF, cefoperazone-sulbactam; CFZ, cefazolin; CXM, cefuroxime; CRO, ceftriaxone; FEP, cefepime; FOX, cefoxitin; IPM, imipenem; MEM, meropenem; ETP, ertapenem; GEN, gentamicin; AMK, amikacin; ATM, aztreonam; TOB, tobramycin; CIP, ciprofloxacin; LEV, levofloxacin; SXT, trimethoprim/sulfamethoxazole; TGC, tigecycline; COL, colistin.