Research Article
Enzymatic Activity and Horizontal Gene Transfer of Heavy Metals and Antibiotic Resistant Proteus vulgaris from Hospital Wastewater: An Insight
Table 10
Drug-likeness properties of the different drugs used in this study.
| S. no | Compounds | Molecular weight | No. of HBA | No. of HBD | MolLogP | Drug-likeness model score: |
| 1. | Amoxicillin | 365.10 | 7 | 5 | 0.05 | 1.39 | 2. | Chloramphenicol | 323.02 | 5 | 4 | 0.17 | 0.93 | 3. | Ampicillin | 349.11 | 6 | 4 | 0.31 | 1.11 | 4. | Erythromycin | 733.46 | 14 | 5 | 1.38 | 1.48 | 5. | Gentamycin | 477.32 | 11 | 12 | −5.08 | 0.85 | 6. | Methicillin | 380.10 | 7 | 2 | 2.41 | 0.29 | 7. | Nalidixic acid | 232.08 | 4 | 1 | 1.23 | 0.82 | 8. | Neomycin | 614.31 | 19 | 19 | −12.21 | 0.97 | 9. | Penicillin | 334.10 | 5 | 2 | 2.55 | 0.80 | 10. | Ciprofloxacin | 331.13 | 4 | 2 | 1.29 | 0.93 | 11. | Kanamycin | 484.24 | 15 | 15 | −9.45 | 0.95 | 12. | Nitrofurazone | 114.03 | 3 | 1 | −0.76 | −1.23 | 13. | Ofloxacin | 361.14 | 5 | 1 | 1.21 | 1.20 | 14. | Polymixin B | 1202.75 | 18 | 23 | −7.48 | −1.10 | 15. | Tetracycline | 444.15 | 9 | 7 | −1.17 | 1.43 |
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No. of HBA: no. of hydrogen bond acceptor. No. of HBD: no. of hydrogen bond donor.
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