Research Article

Anti-Biofilm Effect of Ampicillin-Loaded Poly (Lactic-co-glycolic Acid) Nanoparticles Conjugated with Lysostaphin on Methicillin-Resistant Staphylococcus aureus

Table 2

The PLGA-AMP formulation’s technological features include average diameter, PDI, and zeta potential throughout the stability study (means ± SD, n = 3).

FormulationTechnological parametersTime (months)
0246812

PLGA-AMP-LYS (F4)Size (nm)301.9 ± 32304.3 ± 34307.8 ± 32312.5 ± 31486.5 ± 36502.6 ± 43
PDI0.261 ± 0.0100.262 ± 0.0140.264 ± 0.0110.274 ± 0.0170.278 ± 0.0120.295 ± 0.016
ZP (mV)−19.2 ± 3.4−18.6 ± 3.2−18.4 ± 2.2−18.8 ± 4.6−17.8 ± 3.8−16.2 ± 4.3

Zeta potential.