Research Article

Anti-Biofilm Effect of Ampicillin-Loaded Poly (Lactic-co-glycolic Acid) Nanoparticles Conjugated with Lysostaphin on Methicillin-Resistant Staphylococcus aureus

Table 3

Results of MIC.

MIC value (μg/mL) 150-100-50-25-15-5-0.5 (μg/mL)
Time (h)Bacterial strainsPLGA-AMPFree-AMP

24MSSA50 ± 45 ± 1
MRSA100 ± 750 ± 2
Clinical strain100 ± 515 ± 1

48MSSA25 ± 25 ± 1
MRSA100 ± 650 ± 5
Clinical strain50 ± 215 ± 1

72MSSA15 ± 15 ± 1
MRSA50 ± 550 ± 3
Clinical strain15 ± 130 ± 1