Research Article

EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method

Table 2

Correlation of EGFR mutation status between tissue and plasma samples before EGFR-TKI treatment.

⁢Pretreatment plasma: P0Total
PositiveNegative

Pretreatment tissue
 Positive19524
 Negative066

Total191130

Sensitivity, 79.2%; specificity, 100%.