The Consumption of Bicarbonate-Rich Mineral Water Improves Glycemic Control
Table 3
Results of MSEA: list of metabolite sets/pathways that are significantly different between TW and BMW consumption periods.
Pathway
Total
Hits
Expect
Fold change (hits/expect)
value
FDR
Purine metabolism
45
7
0.98
7.1
<0.001
0.001
Ammonia recycling
18
4
0.39
10.2
<0.001
0.014
Urea cycle
20
4
0.44
9.2
<0.001
0.014
RNA transcription
9
3
0.20
15.3
<0.001
0.014
Intracellular signaling through prostacyclin receptor and prostacyclin
6
2
0.13
15.3
0.006
0.103
Glycolysis
21
3
0.46
6.6
0.009
0.121
Citric acid cycle
23
3
0.50
6.0
0.012
0.133
Methionine metabolism
24
3
0.52
5.7
0.013
0.133
Gluconeogenesis
27
3
0.59
5.1
0.018
0.163
Amino sugar metabolism
15
2
0.33
6.1
0.040
0.290
Mitochondrial electron transport chain
15
2
0.33
6.1
0.040
0.290
Total numbers of metabolites that corresponded in each pathway. Observed numbers of metabolites that derived from given dataset in each pathway. Expected observed numbers of metabolites that are calculated by given dataset in each pathway. False discovery rate (FDR) according to the Benjamini and Hochberg method that was provided by MSEA software.