Neuroprotective Activity of Coptisine from Coptis chinensis (Franch)

Figure 2

Effect of CR main alkaloids on cell viability in SH-SY5Y cells. Cells were pretreated for 24 h with (0–40 μM) of Ber (a), Cop (b), Jat (c), and Pal (d) before the cells were exposed for 2 h to either medium (medium control) or 100 μM t-BOOH (t-BOOH control). Results represent mean cell viability ± SEM of four independent experiments conducted in triplicates. Only treatment with Cop resulted in a significant increase of cell viability. , versus medium or t-BOOH control.

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