Review Article
Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature
Table 1
Characteristics of the included studies.
| Author | Year | Location | Single versus multicenter | , total | , IBD (CD/UC) | , control | Control composition | Mean age, IBD (CD/UC) | Mean age, control |
| Machiels et al. [8] | 2013 | Belgium | Single | 214 | 0/127 | 87 | Healthy controls | 43 | 41.5 | Varela et al. [12] | 2013 | Spain | Single | 176 | 0/116 | 31 | Healthy controls | 40 | 32 | Swidsinski et al. [13] | 2008 | Germany | Single | 422 | 82/105 | 32 | Healthy controls | 35/41 | 40 |
Dörffel et al. [9] | 2012 | Germany | Single | 171 | 50/0 | 25 | Healthy controls | 39 | 48 | Vermeiren et al. [14] |
2012 | Belgium | Single | 12 | 0/6 | 6 | Healthy controls | Not reported | Not reported | Joossens et al. [15] | 2011 | Belgium | Single | 207 | 68/0 | 55 | Healthy controls | Not reported | Not reported | Wang et al. [16] | 2013 | China | Single | 76 | 21/34 | 21 | Healthy controls | Not reported | Not reported | Jia et al. [17] | 2010 | UK | Single | 73 | 20/14 | 18 | Healthy controls | Not reported | Not reported | Sokol et al. [18] | 2009 | France | Single | 133 | 22/13 | 27 | Healthy controls | 37/40 | 36 | Andoh et al. [19] | 2012 | Japan | Multicenter | 188 | 67/0 | 121 | Healthy controls | 30 | 32 | Willing et al. [20] | 2009 | Sweden | Single | 20 | 6/0 | 6 | Healthy controls | Not reported | Not reported |
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IBD: inflammatory bowel disease; CD: Crohn’s disease; UC: ulcerative colitis.
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