Application of Antithrombotic Drugs in Different Age-Group Patients with Upper Gastrointestinal Bleeding

Table 1

Baseline characteristics.

	Young group (270)	Elderly group (443)	value
Female	34 (12.6)	138 (31.2)	<0.001
Age	48.00 [39.00, 55.00]	71.00 [65.00, 80.50]	<0.001
Black stool	209 (77.4)	323 (72.9)	0.212
Haematemesis	113 (41.9)	181 (40.9)	0.855
Comorbidities
CAD	38 (14.1)	150 (33.9)	<0.001
CHF	10 (3.7)	51 (11.5)	0.001
Hypertension	77 (28.5)	274 (61.9)	<0.001
Diabetes	44 (16.3)	176 (39.7)	<0.001
Valvular disease	11 (4.1)	76 (17.2)	<0.001
Oncological disease	13 (4.8)	95 (21.4)	<0.001
Kidney disease	12 (4.4)	60 (13.5)	<0.001
Respiratory diseases	30 (11.1)	184 (41.5)	<0.001
Cirrhosis	25 (9.3)	43 (9.7)	0.948
Atrial fibrillation	0 (0.0)	34 (7.7)	<0.001
Cerebrovascular disease	13 (4.8)	94 (21.2)	<0.001
Laboratory values
WBC	7.36 [5.82, 9.78]	7.43 [5.58, 9.79]	0.604
Hemoglobin	86.00 [73.00, 102.00]	82.00 [70.00, 96.00]	0.018
Platelets	200.00 [163.00, 247.00]	179.00 [130.50, 222.50]	<0.001
Urea nitrogen	6.03 [4.40, 9.05]	7.80 [5.50, 12.05]	<0.001
Calcium	1.98 [1.82, 2.08]	1.93 [1.59, 2.06]	0.013
Creatine kinase	89.00 [62.50, 136.50]	80.00 [52.25, 142.00]	0.097
Globulin	20.38 [17.16, 23.21]	21.58 [17.56, 25.00]	0.007
INR	1.09 [1.05, 1.17]	1.12 [1.05, 1.18]	0.048
Creatinine	75.00 [64.00, 84.25]	78.00 [63.00, 96.00]	0.012
Albumin	34.16 [30.71, 37.29]	32.00 [28.81, 34.37]	<0.001
Physical examination
Heart rate	88.00 [80.00, 95.00]	82.00 [76.00, 90.00]	<0.001
SBP	126.00 [115.00, 137.00]	130.00 [118.00, 141.00]	0.001
Respiratory rate	20.00 [18.00, 22.00]	20.00 [18.00, 21.00]	0.367
Height	72.15 [62.12, 84.00]	65.00 [55.00, 74.60]	<0.001
Weight	172.00 [167.00, 177.00]	168.00 [160.00, 172.00]	<0.001
BMI	24.54 [22.00, 28.34]	24.24 [21.83, 26.25]	0.022

CHF: congestive heart failure; SBP: systolic blood pressure; CAD: coronary artery disease; PVD: peripheral vascular disease; WBC: white blood cell count; INR: international normalized ratio.