Research Article
Risk Factors for Death in Patients with Severe Acute Pancreatitis in Guizhou Province, China
Table 1
Comparison of clinical characteristics between the survival group and the nonsurvival group in patients with SAP.
| | All patients (), (%) | Survivor (), (%) | Nonsurvivor (), (%) | |
| | Gender | | | | 0.62 | | Females | 205 (42.18) | 179 (42.62) | 26 (39.39) | | | Males | 281 (57.82) | 241 (57.38) | 40 (60.61) | | | Age (years) | | | | <0.01 | | Median | 49 | 46 | 56 | | | Range | 7-89 | 7-89 | 27-84 | | | Etiology | | | | | | Biliary | 339 (69.75) | 289 (68.81) | 50 (75.76) | 0.25 | | Hyperlipidemia | 84 (17.28) | 77 (18.33) | 7 (10.61) | 0.12 | | Mixed | 40 (8.23) | 33 (7.86) | 7 (10.61) | 0.45 | | Alcohol | 12 (2.47) | 11 (2.62) | 1 (1.52) | 0.59 | | Trauma | 5 (1.03) | 5 (1.19) | 0(0) | 0.37 | | Idiopathic | 6 (1.23) | 5 (1.19) | 1 (1.52) | 0.82 | | Comorbidity | | | | | | Hypertension | 137 (28.19) | 112 (26.67) | 25 (37.88) | 0.06 | | Diabetes | 100 (20.58) | 80 (19.05) | 20 (30.30) | 0.04 | | Chronic respiratory diseases | 7 (1.44) | 5 (1.19) | 2 (3.03) | 0.24 | | Chronic renal failure | 7 (1.44) | 4 (0.95) | 3 (4.54) | 0.09 | | Unhealthy lifestyle | | | | | | Smoking | 221 (45.47) | 188 (44.76) | 33 (50.00) | 0.43 | | Excessive drinking | 65 (13.37) | 55 (13.10) | 10 (15.15) | 0.65 | | Complication | | | | | | ARDS | 246 (50.62) | 205 (48.81) | 41 (62.12) | 0.04 | | AKI | 148 (30.45) | 102 (24.29) | 46 (69.70) | <0.01 | | Sepsis | 132 (27.16) | 102 (24.29) | 30 (45.45) | <0.01 | | Organic perforation | 13 (2.67) | 8 (1.90) | 5 (7.58) | 0.03 | | Intra-abdominal hemorrhage | 35 (7.20) | 20 (4.76) | 15 (22.73) | <0.01 | | Fluid collection | 134 (27.57) | 108 (25.71) | 26 (37.88) | 0.02 | | Paralytic intestinal obstruction | 4 (0.82) | 3 (0.71) | 1 (1.52) | 1.00 | | ACS | 28 (5.77) | 17 (4.05) | 11 (16.67) | <0.01 | | Organ failure | 268 (55.14) | 210 (50.00) | 58 (87.88) | <0.01 | | Infected pancreatic necrosis | 126 (25.93) | 97 (23.10) | 29 (43.94) | <0.01 | | Medical intervention | | | | | | Mechanical ventilation | 174 (35.80) | 121 (28.81) | 53 (80.30) | <0.01 | | CRRT | 336 (69.14) | 291 (69.29) | 45 (68.18) | 0.86 | | Vasopressin | 162 (33.33) | 110 (26.19) | 52 (78.79) | <0.01 | | Endoscopic therapy | 42 (8.64) | 34 (8.10) | 8 (12.12) | 0.28 | | Percutaneous drainage | 180 (37.04) | 144 (34.29) | 36 (54.55) | <0.01 | | Laparotomy | 21 (4.32) | 10 (2.38) | 11 (16.67) | <0.01 | | Blood transfusion products | 339 (69.75) | 284 (67.62) | 55 (83.33) | 0.01 | | Time from onset of symptoms to ICU admission | 3.0 (1.0, 4.0) | 3.0 (1.0, 4.0) | 3.0 (2.0, 5.0) | 0.14 | | 90-day mortality | 66 (13.58) | | | |
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SAP: severe acute pancreatitis; ARDS: acute respiratory distress syndrome; AKI: acute kidney injury; ACS: abdominal compartment syndrome; CRRT: continuous renal replacement therapy.
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