Research Article
Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions
Table 2
Key downregulated networks and their top-associated genes (NTA) (subnetwork layouts in Figure
7).
| Pathway GO ID | Pathway GO name | Adjusted -value | Top-ranking associated genes |
| GO:0009653 | Anatomical structure morphogenesis | 8.6426-8 | FYN, GDNF, HECW2 | GO:0007167 | Enzyme-linked receptor protein signaling pathway | 0.0000018879 | FYN, SMAD9 | GO:0030154 | Cell differentiation | 0.0000030284 | CAND1, FYN, GDNF, HECW2, NMT | GO:0048731 | System development | 0.0000031743 | FYN, GDNF, HECW2, NMT | GO:0030335 | Positive regulation of cell migration | 0.0004 | TRIP6 | GO:0071363 | Cellular response to growth factor stimulus | 0.0002 | FYN, SMAD9 | GO:0045860 | Positive regulation of protein kinase activity | 0.0001 | FYN |
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