Application of Laser-Induced Bone Therapy by Carbon Dioxide Laser Irradiation in Implant Therapy
Figure 2
Comparison of osteoid formation in the bone marrow space in the laser-irradiated group and bur-injured group 5 days after treatment. (a) laser-irradiated tibia. Energy density = 88.2 J/cm2, (output: 1.0 W, irradiation time: 2 sec). (b) laser-irradiated tibia. Energy densities = 220.5 J/cm2, (output: 1.0 W, irradiation time: 5 sec). (c) laser-irradiated tibia. Energy densities = 441.0 J/cm2, (output: 1.0 W, irradiation time: 10 sec). (d) laser-irradiated tibia. Energy densities = 661.5 J/cm2, (output: 1.0 W, irradiation time: 15 sec). (e) bur-injured tibia. (a–d) laser-irradiated tibia showed an ablation defect, carbon deposits, and numerous empty osteocytic lacunae. Moreover, newly formed trabecular bone was observed on the marrow side of the laser-treated site (a–c). (e) bur-injured tibia showed a slight amount of reactive bone formation on the endosteal surface. H&E stain with 40x magnification. Bar = 200 μm. Arrow indicates laser-irradiated or bur-injured site. Arrow heads indicate osteoid formation site.
