Application of Laser-Induced Bone Therapy by Carbon Dioxide Laser Irradiation in Implant Therapy
Figure 5
H&E staining observation. (a, d): 5 days after implantation (10 days after sham operation or laser irradiation). (b, e): 10 days after implantation (15 days after sham operation or laser irradiation). (c, f): 20 days after implantation (25 days after sham operation or laser irradiation). (a–c): control group tibia. (d–f): laser group tibia. In the early healing period (10 days after injury), in the control group, there was limited bone formation around the implant body, while in the laser group, there was obvious bone formation along the inserted implant. Fifteen days after injury, in the control group, tibia showed little osteoid formation around the implant body. In the laser group, thick and abundant bone formation was evident along the inserted implant body. Twenty-five days after injury, in the control group, tibia showed newly formed cortical bone, but the trabecular bone was thinner than that in the laser group tibia. In the laser group, thick cortical bone was connected to the previously existing cortex. H&E stain with 40x magnification. c: cortical bone, i: implant cavity, nb: newly formed bone, bar = 200 μm.
