Transmembrane and Ubiquitin-Like Domain-Containing 1 Promotes Glioma Growth and Indicates Unfavorable Prognosis

Table 2

Univariate analysis for overall survival of glioma patients.

Variables	Patients ()	Overall survival		value
		Median (months)	3-year OS
Gender				0.208
Female	42	37.0	51.8%
Male	67	23.0	39.1%
Age (years)				0.292
≤50	54	22.0	47.2%
>50	55	33.0	40.3%
Tumor size				0.296
≤5.0 cm	72	35.0	47.4%
>5.0 cm	37	17.0	37.2%
WHO grade				<0.001
Grade II	23	65.0	73.9%
Grade III	41	42.0	53.8%
Grade IV	45	15.0	20.5%
Karnofsky score				0.942
≤90	72	32.0	43.2%
>90	37	34.0	45.9%
Surgery				0.008
GTR	48	46.0	57.7%
STR	37	22.0	40.5%
PR/biopsy	24	17.0	19.8%
TMUB1 mRNA level				<0.001
Low	53	48.0	66.4%
High	56	15.0	23.1%

Statistically significant by log-rank test. Abbreviations: GTR: gross total resection; STR: subtotal resection; PR: partial resection; TMUB1: transmembrane and ubiquitin-like domain-containing 1.