Transcription Analysis of the THBS2 Gene through Regulation by Potential Noncoding Diagnostic Biomarkers and Oncogenes of Gastric Cancer in the ECM-Receptor Interaction Signaling Pathway: Integrated System Biology and Experimental Investigation

Table 4

List of significant upregulated genes in the ECM-receptor interaction pathway.

Symbol	Rank in gene list	Rank metric score	Running ES
THBS2	13	1.38	0.0489
SPP1	17	1.317	0.0962
COL6A2	28	1.222	0.1396
ITGA5	54	1.079	0.1771
THBS4	62	1.045	0.2143
THBS1	130	0.86	0.2417
COMP	166	0.811	0.269
COL11A1	204	0.764	0.2945
ITGA7	212	0.753	0.3212
FN1	224	0.739	0.3472
TNC	256	0.703	0.3709
COL4A4	315	0.663	0.3917
COL6A3	367	0.629	0.4116
COL4A1	561	0.537	0.4208
COL1A2	741	0.481	0.4287
ITGA11	751	0.479	0.4455
COL5A3	765	0.476	0.4619
COL4A2	842	0.457	0.4743
COL5A1	863	0.451	0.4895
VWF	907	0.443	0.5032
SV2A	909	0.443	0.5191
COL5A2	1021	0.421	0.5284
LAMA5	1058	0.414	0.5414
SDC3	1162	0.396	0.5502
COL6A1	1174	0.393	0.5638
LAMA4	1290	0.374	0.5712
HSPG2	1382	0.361	0.5793
LAMC1	1600	0.332	0.5799
ITGA1	1713	0.319	0.5855
SV2B	1770	0.313	0.5938
TNR	1793	0.31	0.6038
COL1A1	1813	0.307	0.6138
COL3A1	1995	0.285	0.6146
LAMA2	2304	0.257	0.6076
THBS3	2416	0.248	0.6107
RELN	2423	0.248	0.6193
CD44	2458	0.245	0.6264
IBSP	2731	0.225	0.6202
TNN	2747	0.225	0.6275