OSM May Serve as a Biomarker of Poor Prognosis in Clear Cell Renal Cell Carcinoma and Promote Tumor Cell Invasion and Migration

Figure 4

Analysis of the effect of OSM expression on the function of ccRCC cells. (a) Effect of the OSM high expression group and control group on the proliferation of ccRCC cells by using the CCK8 experiment ( value < 0.05). (b–d) Effect of the OSM high expression group versus the control group on ccRCC cell invasion and migration by using the Transwell experiment ( value < 0.05). (e–h) Effect of OSM expression in ccRCC on the expression of tumor metastasis-related molecules such as E-cadherin, N-cadherin, and vimentin by using Western blotting experiment. (i–l) Effect of OSM expression in ccRCC on the expression of E-cadherin and vimentin by immunofluorescence assay. Scale bar, 50 μm. value < 0.05, value < 0.01, and value < 0.001.

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