Review Article
Thromboangiitis Obliterans (Buerger’s Disease)—Current Practices
Table 3
Diagnostic investigation for Buerger’s disease.
| Blood count | | Liver function | | Renal function | | Fasting blood sugar | | Erythrocyte sedimentation rate | | C-reactive protein | | Antinuclear antibodies | | Rheumatoid factor | | Complementary measurements | | Anticentromere antibodies (for CREST) | | Anti-Scl-70 antibodies (for scleroderma) | | Antiphospholipid antibodies | | Lipid profile | | Urinalysis | | Toxicology screen for cocaine and cannabis | | Cryoproteins | | Segmental arterial Doppler pressures | | Arteriography | | Echocardiography (to exclude source of emboli) | | Computed tomography (to exclude potential source of emboli) | | Biopsy (In proximal artery involvement or unusual locations) | | Complete thrombophilia screen: proteins G and S, antithrombin III, factor V Leiden, prothrombin 20210, and homocysteinemia | | Hand radiographs (to exclude calcinosis) | |
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CREST Calcinosis, Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. *Adapted from [43].
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