Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion

Figure 3

Fold expression of (a) IL-1β, (b) TNF, (c) Csf1, (d) CX3CL1, and (e) CX3CR1 in NP in the three groups: NP in contact with dorsal nerve roots for 180 minutes (NP), NP in contact with dorsal nerve roots for 180 minutes together with minocycline (NP+MC), NP in contact with neck fat tissue for 180 minutes (), and native nucleus pulposus (). , , , one-way ANOVA, Tukey’s post hoc test.

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