OMICS Approaches Evaluating Keloid and Hypertrophic Scars

Table 3

Gene association for keloid and hypertrophic scars in different populations.

Gene association	Observations
Codons 10, 25, and 263 and for −509 and −800 single nucleotide polymorphisms of the TGF-β1 gene	Keloid/HTS patients and controls for codons were not statistically significant for genotype or allele occurrence [51]
Region rs873549 on chromosome 1q41	Keloid only [56].
rs1511412 at 3q22.3	Keloid only. LOC389151, a hypothetical gene located 24 kb telomeric to rs1511412, and FOXL2 gene association [56].
rs8032158 at 15p21.3	Keloid only. NEDD4 gene association [56].
HLA-DRB104, 09, 12 and 15. HLA-DRB115	Predisposition to keloids [60]