Review Article

OMICS Approaches Evaluating Keloid and Hypertrophic Scars

Table 5

Proteins observed in normal skin, keloid tissue and in both normal and keloid tissue using 2D Gel Electrophoresis [70].

Proteins observed only in normal skin [70]Proteins observed only in keloids [70]Proteins observed in both normal skin and keloids [70]

Triosephosphate isomerase 1Tropomyosin 1 alpha chain isoform 5Alpha 1‐antitrypsin
Heat shock protein 27Smooth muscle and nonmuscle myosin alkali light chain isoform 1Chloride intracellular channel 1
Heat shock 70 kDa protein 8 isoform 2 variantProfilin 1Proline arginine‐rich end leucine‐rich repeat protein precursor
Eukaryotic translation initiation factor 5ARho GDP dissociation inhibitor alphaCarbonic anhydrase 1
Alpha crystalline B chainActin‐related protein 2 isoform bFibrinogen gamma chain
Keratin 10Gelsolin‐like capping proteinS100A10
Keratin 1Transgelin (SM22)Chain D# human β‐tryptase
Keratin type II cytoskeletal 2 epidermalAlpha 1 type I collagen preproprotein
Carboxy‐propeptide of alpha 1 (III) procollagen
Carbonic anhydrase II mutant E117q holo formAlpha‐1 type III collagen
TransferrinType I collagen
Calmodulin 3Collagen type V alpha 1
Haptoglobin Hp2Ferritin heavy chain
Chain D deoxy Rhb1.1 (recombinant haemoglobin)Ferritin heavy polypeptide 1
Fibrinogen beta chainHaemoglobin‐delta
Gelsolin isoform b
Gelsolin isoform aSerum albumin precursor
Prostatic binding proteinRas‐related nuclear protein (RAN)
Manganese superoxide dismutaseS100A4, S100A8,S100A9
Complement component 3Thioredoxin/thiol‐redox
Immunoglobulin kappa chain V-III region B6Peroxiredoxin I
Mast cell tryptase β III
Macrophage migration inhibitory factor (MIF) chain C
Pigment epithelium‐derived factor
Asporin
Galectin‐1 chain A:
Stratifin (14‐3‐3 sigma)
Maspin (serine/cysteine proteinase inhibitor)
Eukaryotic translation initiation factor 5A isoform I variant a (eIF5A‐1)