OMICS Approaches Evaluating Keloid and Hypertrophic Scars

Table 6

Comparison of upregulated and downregulated proteins in hypertrophic scars compared to normal skin using iTRAQ labeling [71].

Up regulated proteins [71]	Down regulated Proteins [71]
Cartilage oligomeric matrix protein	Inner membrane protein, mitochondrial (mitofilin)
Fibromodulin	Malate dehydrogenase 2, NAD (mitochondrial)
Asporin	Calpastatin
Pleiotrophin	Pyruvate kinase muscle 2
Collagen type XII alpha 1	Dynein, cytoplasmic 1, heavy chain 1
Tenomodulin	Integrin β4
Peptidylprolyl isomerase B (cyclophilin B)	Transketolase
Collagen, type V, alpha 1	H1 histone family, member 0
Thrombospondin 1