Research Article

The Association of Complements, TGF-β, and IL-6 with Disease Activity, Renal Damage, and Hematological Activity in Patients with Naïve SLE

Table 1

Patient’s characteristics.

Characteristics (n/mean ± SD/median (95% CI))

Sex (female : male)30 : 0
Age31.3 ± 10.5 years
SLAM score29.30 ± 3.88
BUN14 (11–19) mg/dL
Creatinine0.725 (0.54–1.20) mg/dL
Proteinuria
 Unremarkable (0)5
 Moderate (+1 and +2)19
 Severe (+3 and +4)6
Leukocyte8056 ± 3442 cells/μL
Platelet190500 (52000–305000) cells/μL
Hematocrit21.96 ± 6.578%
ESR61.83 ± 38.18 mm/hour
Hemoglobin7.13 ± 2.32 g/dL
Lymphocyte967.9 ± 427.8 cells/μL
CRP7.84 (3.20–26.21) mg/L
C328.88 ± 12.98 mg/dL
C415.25 (7.60–20.60) mg/dL
TGF-β35 ± 7.02 ng/mL
IL-6200.6 (127.6–300.5) pg/mL
Anti-dsDNA155.32 ± 186.10 IU/mL
ANA test86.61 (65.50–184.6)

SLAM, systemic lupus activity measurement; BUN, blood urea nitrogen; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; C3, complement 3; C4, complement 4; TGF-β, transforming growth factor-beta; IL, interleukin; dsDNA, double-stranded DNA; ANA, antinuclear antibody.