Skin Cell and Tissue Responses to Cross-Linked Hyaluronic Acid in Low-Grade Inflammatory Conditions

Figure 5

Representative HES coloration skin (×20) in systemic low-grade inflammatory mice 24 h after an acute intradermal injection (20 µl) of the vehicle control (a), VYC-15L fragments (b), VYC-15L (c), HYC-24L + fragments (d), and HYC-24L+ (e). e = epidermis, d = dermis, hy = hypodermis, i = inflammation, and HA = hyaluronic acid. Hyaluronic acid is colored in dark violet, extracellular elements in yellow, and nuclei of cells in purple.