N-Acetylcysteine Decreases Myocardial Content of Inflammatory Mediators Preventing the Development of Inflammation State and Oxidative Stress in Rats Subjected to a High-Fat Diet

Figure 1

The concentration of arachidonic acid in the (a) phospholipid (PL), (b) triacylglycerol (TAG), (c) diacylglycerol (DAG), and (d) free fatty acid (FFA) fractions after eight-week N-acetylcysteine (NAC) treatment in the plasma of rats fed a standard diet (control) or a high-fat diet (HFD). The arachidonic acid content in the selected lipid fractions was examined by the Gas-Liquid Chromatography (GLC) method. The data are expressed as mean ± standard deviation (SD) and based on ten independent determinations (n = 10). The significant differences were assessed by two-way ANOVA followed by a respective post hoc test (Tukey’s test and t-test). , significant difference compared to the control group; ^#, significant difference compared to the HFD group.

(a)

(b)

(c)

(d)