Review Article
Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review
Table 1
Analysis of the risk of bias of observational studies with the ACROBAT-NRSI tool.
| | Authors (years) | Participants selection bias | Bias in measurement of interventions | Bias due to confounding | Bias in outcome measurement | Bias in selection of reported results |
| | Kalkan et al. (2018) [19] | Low risk | Low risk | Low risk | Low risk | Low risk | | Vamvini et al. (2013) [20] | Uncertain risk | Low risk | Uncertain risk | Low risk | Low risk | | Anaszewicz et al. (2019) [21] | Uncertain risk | Low risk | High risk | Uncertain risk | Low risk | | El-Lebedy et al. (2018) [22] | Low risk | Low risk | Low risk | Low risk | Low risk | | Bonfante et al. (2017) [23] | Uncertain risk | Uncertain risk | Uncertain risk | High risk | Uncertain risk | | Belviranli et al. (2016) [24] | Uncertain risk | Low risk | Low risk | Low risk | Low risk | | Abd El-Mottaleb et al. (2019) [25] | Low risk | High risk | Uncertain risk | Low risk | Low risk | | Emanuele et al. (2014) [26] | Low risk | Low risk | Low risk | Low risk | Low risk | | Deng (2016) [27] | Uncertain risk | Low risk | Uncertain risk | High risk | Low risk | | Shen et al. (2017) [28] | Low risk | Low risk | Low risk | Low risk | Low risk | | Saadeldin et al. (2018) [29] | Low risk | Low risk | Low risk | Uncertain risk | Low risk | | Khorasani et al. (2019) [30] | Low risk | Low risk | Low risk | Low risk | Low risk | | Tang et al. (2019) [31] | Low risk | Uncertain risk | Uncertain risk | Low risk | Low risk | | Hou et al. (2015) [32] | Uncertain risk | Low risk | Uncertain risk | Low risk | Low risk | | Campolo et al. (2020) [33] | Low risk | Uncertain risk | Low risk | Low risk | Low risk | | Sahin-Efe et al. (2018) [34] | Low risk | Low risk | Uncertain risk | Low risk | Low risk | | Sesti et al. (2014) [35] | Low risk | Low risk | Uncertain risk | Low risk | Low risk | | Tu et al. 2018 [36] | Low risk | Low risk | Low risk | Uncertain risk | Low risk | | Shi et al. (2016) [37] | Uncertain risk | Low risk | Low risk | Uncertain risk | Low risk | | Ko et al. (2016) [38] | Low risk | Uncertain risk | Low risk | Low risk | Low risk | | Aronis et al. (2015) [39] | Low risk | Low risk | Low risk | Low risk | Low risk | | Sanchis-Gomar and Perez-Quilis (2014) [11] | Low risk | Low risk | Low risk | Low risk | Low risk | | Silvestrini et al. (2019) [40] | Low risk | Low risk | Low risk | Low risk | Low risk | | Stengel et al. (2013) [41] | Uncertain risk | Low risk | Low risk | Low risk | Low risk | | Shoukry et al. (2016) [42] | Low risk | Low risk | Low risk | Low risk | Low risk | | Hsieh et al. (2018) [43] | Low risk | Low risk | Low risk | Low risk | Low risk |
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Source: own authorship.
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