Irisin and Cardiometabolic Disorders in Obesity: A Systematic Review

Table 2

Analysis of the risk of bias of clinical trials studies with the Cochrane Collaboration risk of bias (RoB2) tool.

Authors (years)	Bias arising from randomization process	Allocation sequence concealment	Blinding of participants and personnel	Blinding of outcomes assessment	Attrition bias	Reporting bias	Other biases
Agh et al. (2017) [44]	Low risk	Low risk	Low risk	Uncertain risk	Low risk	Low risk	Uncertain risk
Liu et al. (2016) [45]	High risk	Uncertain risk	Uncertain risk	Low risk	Low risk	Uncertain risk	Low risk
Huerta et al. (2015) [46]	Low risk	Low risk	Low risk	Low risk	Low risk	Low risk	Uncertain risk
Panagiotou et al. (2014) [47]	Low risk	Uncertain risk	Uncertain risk	Low risk	High risk	Low risk	Low risk

Source: own authorship.