In Vitro and In Vivo Anti-Inflammatory Properties of the Hydroethanolic Extract of the Roots of Vernonia guineensis (Asteraceae)

Table 4

Effect of the hydroethanolic extract of V. guineensis on hematology.

Treatment	Dose (mg/kg)	White blood cells (10^3/µl)	Red blood cells (10^6/µL)	Hemoglobins (g/dl)	Hematocrit (%)	Platelets (10^9/L)
Normal control	—	5.64 ± 0.44	5.50 ± 0.31	13.90 ± 0.36	50.15 ± 4.45	292.40 ± 29.74
Negative control	—	11.46 ± 0.69^λ	3.25 ± 0.15^λ	10.14 ± 0.31^λ	43.72 ± 0.93	394.20 ± 11.28^β
Diclofenac	5	9.64 ± 0.55^λ	3.42 ± 0.24^λ	11.56 ± 0.48^α	46.14 ± 1.62	328.80 ± 9.62
HEE	62.5	8.66 ± 0.30^λb	3.63 ± 0.22^λ	9.44 ± 0.68^λ	37.24 ± 1.79^β	372.40 ± 10.30^α
	125	7.70 ± 0.36^c	4.37 ± 0.11^αa	11.92 ± 0.67	42.56 ± 2.56	328.00 ± 14.08
	250	5.88 ± 0.12^c	5.29 ± 0.18^c	13.68 ± 0.35^c	50.12 ± 0.92	298.80 ± 22.86^a

Each value represents the mean ± standard error on the mean of 5 animals and analyzed by one-way ANOVA followed by Tukey’s post test. ^a, ^b and ^c compared with the negative control and ^α, ^β, and ^λ compared with the neutral control.