Research Article

Autoimmune Regulator Gene Polymorphisms in Egyptian Systemic Lupus Erythematosus Patients: Preliminary Results

Table 1

Genotype and allele frequency of AIRE rs2075876 in the lupus patients and control groups.

Patients ()Control () valueOR (95% CI)

GenotypeAA, (%)11 (11.1)8 (7.3)0.159
AG, (%)36 (36.4)30 (27.3)
GG, (%)52 (52.5)72 (65.5)
ModelsDominantAA+AG, (%)47 (47.5)38 (34.5)0.0571.7 (1-3)
GG, (%)52 (52.5)72 (65.5)
RecessiveAA, (%)11 (11.1)8 (7.3)0.3351.6 (0.6-4.1)
GG+AG, (%)88 (88.9)102 (92.7)
Patients ()Control ()
AlleleA, (%)58 (29.3)46 (20.9)
0.0481.6 (1-2.4)
G, (%)140 (70.7)174 (79.1)

The comparisons were done using the Chi-square tests. : number; OR: odds ratio; CI: confidence interval.