Evaluation of Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis: A Single Center Experience

Table 5

Changes in laboratory values from last visit before onset of MAS to development of MAS according to 2016 MAS criteria ().

	Normal range	Last visit before MAS	Onset of MAS	value
Ferritin, μg/L	7-152	767 (650-1898)	4049 (2245-9753)	0.018
PLT, ×10^9/L	135-435	381 (233-578)	210 (134-286)	0.018
ALT, U/L	5-45	12 (10-33)	128 (21-144)	0.128
WBC, ×10^9/L	4.4-16.2	17.4 (6-23.7)	7.1 (5.4-8.4)	0.043
Neutrophil count, ×10^9/L	1.20-9.60	13 (4-16.6)	4.1 (3.7-4.5)	0.028
ESR, mm	0-20	60 (28-79)	45 (32-90)	0.866
CRP, mg/L	0-8.0	51.7 (30.1-150.8)	34 (8.2-56.1)	0.128
Hb, mmol/L	6.0-9.9	7.2 (7.0-7.5)	7.0 (6.4-7.4)	0.496

PLT: platelets; ALT: alanine aminotransferase; WBC: white blood cells; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; Hb: hemoglobin. Values are given as median with interquartile range in parenthesis. values are obtained using Wilcoxon signed rank test for paired comparison.