Evaluation of Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis: A Single Center Experience
Table 6
Sensitivity and specificity of components of 2016 MAS classification criteria.
SJIA with MAS
SJIA without MAS
value
Sensitivity (%)
Specificity (%)
Positive predictive value (%)
Negative predictive value (%)
μg/L
8/8
10/18
0.023
100 (63.1-100)
44.4 (21.5-69.2)
44.4 (34.6-54.7)
100
/L
4/8
1/24
0.002
50 (15.7-84.3)
95.8 (78.9-99.9)
80 (34.2-96.9)
85.2 (74.1-92.0)
μmol/L
5/7
2/11
0.024
71.4 (29-96.3)
81.8 (48.2-97.7)
71.4 (39.6-90.5)
81.8 (57.5-93.8)
mmol/L
6/7
3/12
0.011
85.7 (42.1-99.6)
75 (42.8-94.5)
66.7 (41.8-84.8)
90 (58.8-98.3)
U/L
5/8
3/24
0.005
62.5 (24.5-91.5)
87.5 (67.6-97.3)
62.5 (33.7-84.5)
87.5 (73.9-94.6)
PLT: platelets; ALT: alanine aminotransferase. Sensitivity, specificity, positive predictive values, and negative predictive values are expressed as percentages with 95% confidence interval in parenthesis. values are obtained using Pearson chi-square test.
