International Journal of Rheumatology / 2022 / Article / Tab 2 / Research Article
Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables Table 2 Comparison of some sociodemographic and pharmacological variables between women and men diagnosed with autoimmune idiopathic inflammatory myopathies in Colombia.
Variables Women Men % % Age, median (IQR) 53.0 (41.0-64.0) 53.0 (41.0-64.0) 0.054 Type of inflammatory myopathy — — — — — Overlap myositis 173 36.3 38 19.5 <0.001 Polymyositis 118 24.8 80 41.0 <0.001 Other dermatomyositis 96 20.2 49 25.1 0.156 Dermatopolymyositis 86 18.1 27 13.8 0.185 Juvenile dermatomyositis 3 0.6 1 0.5 1.000 Comorbidities 397 83.4 138 70.8 <0.001 Arterial hypertension 187 39.3 62 31.8 0.068 Diabetes mellitus 104 21.8 35 17.9 0.258 Hypothyroidism 96 20.2 28 14.4 0.078 Rheumatoid arthritis 97 20.4 22 11.3 0.005 Chronic pain 61 12.8 16 8.2 0.089 Infections 119 25.0 38 19.5 0.126 Pharmacotherapy 441 92.6 173 88.7 0.097 Systemic glucocorticoids 380 79.8 147 75.4 0.203 Prednisolone 305 64.1 109 55.9 0.048 Prednisone 117 24.6 32 16.4 0.021 Dexamethasone 90 18.9 29 14.9 0.214 Methylprednisolone 43 9.0 9 4.6 0.052 Pulses 9 1.9 1 0.5 0.295 Deflazacort 35 7.4 12 6.2 0.581 Betamethasone 22 4.6 8 4.1 0.768 Hydrocortisone 9 1.9 1 0.5 0.295 Conventional DMARDs 366 76.9 131 67.2 0.009 Azathioprine 238 50.0 89 45.6 0.305 Methotrexate 181 38.0 61 31.3 0.099 Chloroquine 82 17.2 23 11.8 0.079 Hydroxychloroquine 27 5.7 5 2.6 0.086 Sulfasalazine 5 1.1 1 0.5 0.678 Leflunomide 3 0.6 2 1.0 0.631 Immunosuppressants 43 9.0 18 9.2 0.936 Mycophenolate 17 3.6 7 3.6 0.991 Cyclosporine 16 3.4 5 2.6 0.590 Cyclophosphamide 15 3.2 6 3.1 0.960 Human immunoglobulin 4 0.8 1 0.5 1.000 Biological DMARDs 19 4.0 6 3.1 0.570 Rituximab 17 3.6 4 2.1 0.464 Others ( ) ^ 2 0.4 2 1.0 0.584 Comedications — — — — — Analgesics 328 68.9 121 62.1 0.087 Antiulcer 312 65.5 101 51.8 0.001 Antihypertensives and diuretics 216 45.4 72 36.9 0.045 Nonsteroidal anti-inflammatory drugs 204 42.9 79 40.5 0.577 Antihistamines 189 39.7 53 27.2 0.002
IQR: interquartile range; DMARD: disease-modifying antirheumatic drugs.
Mann–Whitney
test.
Fisher’s exact test. ^Others: adalimumab, abatacept, belimumab, and certolizumab.