Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables

Table 4

Comparison of some sociodemographic and pharmacological variables between cities and municipalities of patients diagnosed with autoimmune idiopathic inflammatory myopathies in Colombia.

Variables	Capital city		Intermediate municipality
		%		%
Age, median (IQR)	56.0 (43.0-67.0)		57.0 (41.0-65.0)		0.550
Women	367	72.2	109	66.9	0.189
Type of inflammatory myopathy	—	—	—	—	—
Overlap myositis	163	32.1	48	29.4	0.528
Polymyositis	150	29.5	48	29.4	0.985
Other dermatomyositis	96	18.9	49	30.1	0.003
Dermatopolymyositis	95	18.7	18	11.0	0.023
Juvenile dermatomyositis	4	0.8	0	0.0	0.577
Comorbidities	410	80.7	125	76.7	0.266
Arterial hypertension	189	37.2	60	36.8	0.928
Diabetes mellitus	102	20.1	37	22.7	0.473
Hypothyroidism	100	19.7	24	14.7	0.156
Rheumatoid arthritis	93	18.3	26	16.0	0.493
Chronic pain	68	13.4	9	5.5	0.006
Infections	123	24.2	34	20.9	0.379
Pharmacotherapy	474	93.3	140	85.9	0.003
Systemic glucocorticoids	397	78.1	130	79.8	0.664
Prednisolone	312	61.4	102	62.6	0.791
Prednisone	119	23.4	30	18.4	0.180
Dexamethasone	81	15.9	38	23.3	0.032
Methylprednisolone	41	8.1	11	6.7	0.583
Pulses	7	1.4	3	1.8	0.712
Deflazacort	38	7.5	9	5.5	0.394
Betamethasone	17	3.3	13	8.0	0.013
Hydrocortisone	7	1.4	3	1.8	0.712
Conventional DMARDs	397	78.1	100	61.3	<0.001
Azathioprine	260	51.2	67	41.1	0.025
Methotrexate	195	38.4	47	28.8	0.027
Chloroquine	83	16.3	22	13.5	0.385
Hydroxychloroquine	28	5.5	4	2.5	0.139
Sulfasalazine	4	0.8	2	1.2	0.637
Leflunomide	1	0.2	4	2.5	0.014
Immunosuppressants	46	9.1	15	9.2	0.955
Mycophenolate	19	3.7	5	3.1	0.687
Cyclosporine	13	2.6	8	4.9	0.134
Cyclophosphamide	18	3.5	3	1.8	0.437
Human immunoglobulin	4	0.8	1	0.6	1.000
Biological DMARDs	20	3.9	5	3.1	0.610
Rituximab	16	3.1	5	3.1	0.958
Others ()^	4	0.8	0	0.0	0.577
Comedications	—	—	—	—	—
Analgesics	335	65.9	114	69.9	0.346
Antiulcer	312	61.4	101	62.0	0.901
Antihypertensives and diuretics	218	42.9	70	42.9	0.994
Nonsteroidal anti-inflammatory drugs	208	40.9	75	46.0	0.254
Antihistamines	183	36.0	59	36.2	0.968

IQR: interquartile range; DMARD: disease-modifying antirheumatic drugs. Mann–Whitney test. Fisher’s exact test. ^Others: adalimumab, abatacept, belimumab, and certolizumab.