Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables

Table 5

Comparison of some sociodemographic and pharmacological variables between the types of affiliation regimen to the health system of patients diagnosed with autoimmune idiopathic inflammatory myopathies in Colombia.

Variables	Contributory		Subsidized
		%		%
Age, median (IQR)	58.0 (44.0-67.0)		48.0 (32.5-59.5)		<0.001
Women	415	70.3	61	75.3	0.356
Type of inflammatory myopathy	—	—	—	—	—
Overlap myositis	188	31.9	23	28.4	0.528
Polymyositis	174	29.5	24	29.6	0.980
Other dermatomyositis	124	21.0	21	25.9	0.314
Dermatopolymyositis	100	16.9	13	16.0	0.839
Juvenile dermatomyositis	4	0.7	0	0.0	1.000
Comorbidities	473	80.2	62	76.5	0.446
Arterial hypertension	230	39.0	19	23.5	0.007
Diabetes mellitus	127	21.5	12	14.8	0.162
Hypothyroidism	116	19.7	8	9.9	0.033
Rheumatoid arthritis	105	17.8	14	17.3	0.910
Chronic pain	74	12.5	3	3.7	0.015
Infections	141	23.9	16	19.8	0.409
Pharmacotherapy	547	92.7	67	82.7	0.002
Systemic glucocorticoids	468	79.3	59	72.8	0.183
Prednisolone	375	63.6	39	48.1	0.007
Prednisone	135	22.9	14	17.3	0.256
Dexamethasone	103	17.5	16	19.8	0.612
Methylprednisolone	45	7.6	7	8.6	0.749
Pulses	10	1.7	0	0.0	0.618
Deflazacort	40	6.8	7	8.6	0.538
Betamethasone	28	4.7	2	2.5	0.565
Hydrocortisone	9	1.5	1	1.2	1.000
Conventional DMARDs	448	75.9	49	60.5	0.003
Azathioprine	288	48.8	39	48.1	0.911
Methotrexate	219	37.1	23	28.4	0.125
Chloroquine	92	15.6	13	16.0	0.916
Hydroxychloroquine	28	4.7	4	4.9	1.000
Sulfasalazine	6	1.0	0	0.0	1.000
Leflunomide	5	0.8	0	0.0	1.000
Immunosuppressants	57	9.7	4	4.9	0.166
Mycophenolate	22	3.7	2	2.5	0.757
Cyclosporine	20	3.4	1	1.2	0.497
Cyclophosphamide	19	3.2	2	2.5	1.000
Human immunoglobulin	5	0.8	0	0.0	1.000
Biological DMARDs	22	3.7	3	3.7	1.000
Rituximab	18	3.1	3	3.7	0.732
Others ()^	4	0.7	0	0.0	1.000
Comedications	—	—	—	—	—
Analgesics	393	66.6	56	69.1	0.651
Antiulcer	363	61.5	50	61.7	0.972
Antihypertensives and diuretics	262	44.4	26	32.1	0.036
Nonsteroidal anti-inflammatory drugs	237	40.2	46	56.8	0.005
Antihistamines	211	35.8	31	38.3	0.659

IQR: interquartile range; DMARD: disease-modifying antirheumatic drugs. Mann–Whitney test. Fisher’s exact test. ^Others: adalimumab, abatacept, belimumab, and certolizumab.